The virus attaches to angiotensin converting enzyme (ACE2) protein on human cells. It could have originated from bats or pangolins. -Genomic Study Points to Natural Origin of COVID-19 #coronavirus See Post

Clinical outcome of 55 asymptomatic cases at the time of hospital admission infected with SARS-Coronavirus-2 in Shenzhen, China " 3.6% asymptomatic SARS-CoV-2 infection might take a turn for the worse" - March 2020 Journal of Infectious Disease #coronavirus See Post

The virus spread through all of China in 30 days. "overall case-fatality rate (CFR) was 2.3% (1023 deaths among 44 672 confirmed cases). No deaths occurred in the group aged 9 years and younger, but cases in those aged 70 to 79 years had an 8.0% CFR and cases in those aged 80 years and older had a 14.8% CFR" #coronavirus JAMA 2020 See Post

Five patients on mechanical ventilation improved after receiving plasma from people who recovered from #coronavirus. -JAMA March 27, 2020 See Post

For adults receiving mechanical ventilation who have acute respiratory distress syndrome (ARDS), use of low tidal volume ventilation (4-8 mL/kg of predicted body weight) is recommended and preferred over higher tidal volumes (>8 mL/kg) #coronavirus -JAMA March 26, 2020 See Post

In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir–ritonavir treatment beyond standard care. HIV medications were ineffective in a trial of 200 patients. -NEJM March 2020 #coronavirus See Post